Kandarpa Kumar Saikia

Kandarpa Kumar Saikia

Associate Professor

MSc (JMI) PhD (AIIMS)

Associate Professor

Department of Bioengineering and Technology
Gauhati University, Guwahati, 781014
Email:- kksaikia@gauhati.ac.in

1. Synthesis, characterization and evaluation of anticancer activity of novel bioessential transition metal complexes having tumor targeting and antitumor active ligands

2. Molecular profiling of Acute myeloid leukemia

3. Molecular characterization of clinically important bacterial isolates and evaluation of antibacterial efficacy of some indigenous medicinal plants

Talukdar S, Bayan U, Saikia KK*. In silico identification of vaccine candidates against Klebsiella oxytoca. Computational Biology and Chemistry · 2017; DOI: 10.1016/j.compbiolchem.2017.05.003
 
Bhattacharyya J, Nath S, Saikia KK*, Saxena R, Sazawal S, Barman MP, Kumar D Prevalence and Clinical Significance of FLT3 and NPM1 Mutations in Acute Myeloid Leukaemia Patients of Assam, India. Indian J Hematol Blood Transfus. 2017; doi:10.1007/s12288-017-0821-0
 
Deka B, Sarkar T, Banerjee S*, Kumar A, Mukherjee S, Deka S*, Saikia KK*, Hussain A*. Novel mitochondria targeted copper(II) complexes of ferrocenyl terpyridine and anticancer active 8-hydroxyquinolines showing remarkable cytotoxicity, DNA and protein binding affinity.  Dalton Trans. 2017; 46, 396-409 

Panigrahi MK, Kumar D, Mehta A, Suryavanshi M, Bhurani D, Saikia KK. Novel e8a2 BCR/ABL Fusion Transcript in Case of a Myeloproliferative Neoplasm. Indian J Hematol Blood Transfus.  Indian J Hematol Blood Transfus. 2017; 33: 271-72

Sarma PP, Dutta D, Mirza Z, Saikia KK*, Baishya BK. Point mutations in the DNA binding domain of TP53 contribute to glioma progression and poor prognosis. Mol Biol. 2017; 51: 293-99

Panigrahi MK, Kumar D, Saikia KK, Kapoor G, Mehta A. Outcome of HER2 Testing by FISH Applying ASCO/CAP 2007 and 2013 Guideline in IHC Equivocal Group of Breast Cancer: Experience at Tertiary Cancer Care Centre. South Asian Journal of Cancer. In press
 
Saha RK, Debanath MK, Saikia E, Borah VV, Saikia KK. Use of Tools of NLD in Analysis and Calibration of Cu-doped ZnO Nanoparticles(NPs) for Biological Applications. Advanced Materials Proceedings. 2017; 2(1), 26-31
 
Kumar D, Panigrahi MK, Suryavanshi M, Mehta A, Saikia KK. Quantification of DNA Extracted from Formalin Fixed Paraffin-Embeded Tissue Comparison of Three Techniques: Effect on PCR Efficiency. J Clin Diagn Res. 2016; 10(9): BC01–BC03
 
Borah V V, Saikia K K*, Chandra P, Hazarika N K, Chakravarty R. New Delhi metallo-β-lactamase and extended spectrum β-lactamases co-producing isolates are high in community-acquired urinary infections in Assam as detected by a novel multiplex polymerase chain reaction assay. Indian J Med Microbiol 2016;34:173-82
 
Borah VV, Saikia KK*, Hazarika NK. First report on the detection of OXA-48 β-lactamase gene in Escherichia coli and Pseudomonas aeruginosa co-infection isolated from a patient in a Tertiary Care Hospital in Assam. Indian J Med Microbiol 2016;34:252-3
 
Phukan C, Lahkar M, Ranotkar S, Saikia KK. Emergence of vanA gene among vancomycin-resistant enterococci in a tertiary care hospital of North - East India. Indian J Med Res. 2016; 143(3): 357–361
 
Ravikant, Kumar P, Ranotkar S, Zutshi S, Lahkar M, Phukan C, Saikia KK. Prevalence and identification of extended spectrum β-lactamases (ESBL) in Escherichia coli isolated from a tertiary care hospital in North-East India.Indian J Exp Biol. 2016 Feb; 54(2):108-14.
 
Sarma U, Borah VV, Saikia KK*, Hazariak NK. Screening of Enhydra fluctuans for Phytochemical Composition and Broad-Spectrum Antibacterial Activity against Clinical Bacterial Isolates. Journal of Herbs,Spices & Medicinal Plants. 2016; 22 (4): 300-308
 
Kumar D, Panigrahi MK, Saikia KK, Kapoor G, Mehta A. Molecular analysis of childhood B-acute lymphoblastic leukemia: Identification and prognosis of rare breakpoints. Mol Biol (Mosk). 2015;49(6):944-8
 
Talukdar S, Zutshi S, Prashanth KS, Saikia KK*, Kumar P. Identification of potential vaccine candidates against Streptococcus pneumoniae by reverse vaccinology approach. Applied Biochemistry and Biotechnology. 2014; 172, 3026–3041.  
 
Sarma U, Borah VV, Saikia KK, Hazarika NK. Enhydrafluctuans: A review on its pharmacological importance as a medicinal plant and prevalence and use in North- East India. International Journal of Pharmacy and Pharmaceutical Sciences. 2014; 6 (2), 48-50.  
 
Borah VV, Bora P, Roy M, Saikia KK*. High Prevalence of Antibiotic Resistance in Escherichia coli Isolated from Fecal Sample of Cows and Assessment of Antibacterial Efficacy of Indigenous Medicinal Plants from Assam, India. Austin J Biotechnol Bioeng. 2014; 1(1). 6.
 
Saikia KK*, Borah V, Kalita MC, Lahkar M. Comparative screening of antibacterial and antifungal activity of six ethno-medicinally important plants of Assam Int J Pharm Bio Sci 2013; 4(1): 890 – 898   
 
Kumar P, Nityanand B. Bolshette, Vinayak S. Jamdade, Mundhe NA, Krishan K. Thakur, Saikia KK, Lahkar M. Breast cancer status in India: An overview. Biomedicine & Preventive Nutrition. 2013; 3 (2). 177-183.  
 
Anand JR,Rijhwani H,  Malapatia K, Kumar P, Saikia KK, Lakhar M. Anticancer activity of esculetin via-modulation of Bcl-2 and NF-B expression in benzo[a]pyrene induced lung carcinogenesis in mice. Biomedicine & Preventive Nutrition. 2012; 3 (2). 107-112.    
 
Saikia KK, Das BK, Bewal R, Verma R, Kapil A, Arora NK, Sood S; Characterization of nasopharyngeal isolates of type b Haemophilus influenzae from Delhi: Identification of new sequence types. Indian Journal of Medical Research. 2012; 136. 9-15. 
 
Saikia KK, Das BK, Arora NK, Chandra P. Molecular Typing and Evolutionary Analysis of Haemophilus Influenzae Isolated in Delhi. Ass J Int Med. 2012; 2(2). 11-12.
 
Saikia KK. Seroprevalence and genetic diversity of Streptococcus pneumoniae: Analysis of global data through an in-silico approach. J Ass Sc Soc. 2011; 12-15 
 
Saikia KK, Bewal R, Bansal D, Kapil A, Sood S, Arora NK, Das BK; Multi Locus Sequence Type comparison of invasive and commensal Haemophilus influenzae isolates from Delhi. Indian Journal of Medical Microbiology. 2011; 29(2), 158-160.

BOOKS:

 

1.   Techniques in Molecular Diagnostics: ISBN- 978-93-85516-290

 

2.    Reverse vaccinology:  ISBN- 978-93-85083-23-5

 

LABORATORY GUIDELINES:

 

Co-authored – Laboratory guidelines for HIV Diagnosis in Infants and Children less than 18 months- January 2011 by National AIDS control Organization, India

 

  • Commonwealth Professional Fellowship, 2016-17
  • Junior and Senior Research Fellowships, July 2004, through National Eligibility Test (NET) conducted by Council for Scientific and Industrial Research (CSIR), Govt. of India.
  • Served Society of Young Scientists®, a national forum for young researchers as General Secretary (2006-2007) and Vice President (2007-2008).